"Inactivation of Human Immunodeficiency Virus Type 1 by Ozone in Vitro"
by J. Latino, K.H. Wells, J. Gavalchin, and B. J. Polesz.
excerpted from "BLOOD, the Journal of the American Society of Hematology",
Vol. 78, No.7, October 1, 1991:
"A device was designed to deliver a constant source of given concentration of ozone fluids containing Human Immunodeficiency Virus Type 1 (HIV-1). Ozone was found to inactivate HIV-1 in a dose-dependent manner. Greater than 11 log inactivation was achieved within 2 hours at a concentration of 1,200 ppm ozone. Similar concentrations of ozone had minimal effect on factor VIII activity in both plasma and immunoaffinity-purified preparations of factor VIII treated for the same time period. The data indicate that the antiviral effects of ozone include viral particle disruption, reverse transcriptase inactivation, and/or a perturbation of the ability of the virus to bind to its receptor on target cells. Ozone treatment offers promise as a means to inactivate human retroviruses in human body fluids and blood product preparations."
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Note: The use of Ozone by doctors is illegal in some states in the US so please check local laws, information presented here is for educational, historical, and research purposes only.